3D MODELING OF REACTION-DIFFUSION MECHANISM IN HETEROGENEOUS CELL ARCHITECTURE

Abstract

The manifold cell organization permitted extraneous hydrophobic compounds to react
with the existing compounds inside the cell. The carcinogenic and lipophilic environmental toxins
PAH provoked detrimental and noxious compounds in the interior of the cell. The cell sustained
reaction and diffusion mechanism with those lipophilic compounds. The heterogeneous cell
configuration grew into mosaic by virtue of the membranous architectures in the vicinity of the
cytoplasm. The establishment of those conglomerate cytoplasmic membranous organelles in 2D
axisymmetric geometry was absurd therefore 3D geometry was constructed. The model had been
formulated in ComsolMultiphysics by adopting the homogenization approach. The counter collation of
the simulated results of 3D and 2D axisymmetric model were investigated. The commendable affinity
demonstrated by the results encouraged to extend the model by introducing diminutive cytoplasmic
organelles in addition with more convoluted reaction chains.