ANTVIRAL ACTIVITY OF OLEA EUROPAEA L. AGAINST FOOT AND MOUTH DISEASE VIRUS

Abstract

This research had been conducted to analyze the natural agents for the antiviral activity that utilized essentially and simply in the field or it had the objective to lessen the animals’ carrier condition as well as to decrease infection during an outbreak of disease or infected animals’ quantity. The antiviral and cytotoxic effects of Olea europaea L. against foot and mouth disease virus (FMDV) were observed by using the cell culture technique. FMD virus is considered as the causal agent of the disease which influences domesticated livestock and became a cause of intense sickness that is characterized by low morality, high dismalness of teats, tongue, and nose, fever, vesicular sores on feet, and weakness. It was predicted that the Olea europaea L.’s alcohol leaf extracts had antiviral potent activity at 31.25Hg/mL-250Hg/mL concentration range along with a range of CSP that was fifty-one percent (51%) to sixty-three percent (63%) which followed by chloroforms extract activity in which percentage of cell survival was analyzed fifty-four percent (54%) or fifty-seven (57%) at concentration 31.25 Hg/mL or 62.5 Hg/mL respectively. So, the antiviral activity of Olea europaea L. observed in this research might be due to the presence of oleuropein which inhibited the in vitro infectivity of the Foot and mouth disease virus (FMDV).