A REVIEW ON ASPECTS OF CURRENT PHARMACOTHERAPIES FOR COVID-19

Authors

  • S. Areej
  • M. Ahmad Department of Pharmacology and Toxicology, University of Veterinary and Animal Sciences, Lahore, Pakistan.2Department of Pharmacology,Riphah International University, Lahore, Pakistan
  • G.Abbas Department of Animal Production, Riphah College of Veterinary Sciences, Riphah International University, Lahore, Pakistan
  • A.Majeed Department of Pharmacology and Toxicology, University of Veterinary and Animal Sciences, Lahore, Pakistan
  • B. M.Beg Department of Pharmacology and Toxicology, University of Veterinary and Animal Sciences, Lahore, Pakistan
  • A.Iqbal Department of Pathobiology, Riphah College of Veterinary Sciences, Riphah International University, Lahore, Pakistan
  • A.Basharat Department of Pharmacology and Toxicology, University of Veterinary and Animal Sciences, Lahore, Pakistan.
  • R. M. Z.Mushtaq Lords College of Pharmacy Lahore, Pakistan
  • W.Ahmad Institute of Microbiology, University of Veterinary and Animal Sciences Lahore
  • S.Aroosa Department of Pharmacology and Toxicology, University of Veterinary and Animal Sciences, Lahore, Pakistan
  • S. Jaffery Faculty of Agriculture, University of Agriculture Faisalabad, Pakistan.
  • S. B.Shabbir Institute of Microbiology, University of Veterinary and Animal Sciences Lahore

DOI:

https://doi.org/10.57041/pjs.v74i3.790

Keywords:

COVID-19, therapeutic approaches, antiviral drugs, mechanism of action

Abstract

The novel coronavirus has infected over 609,848,852 individuals throughout the
world with a total death of over 6.5 million since its outbreak in December 2019. Since then many
therapeutic options have been approached and tested in clinical trials as well to find a potential cure or
preventive therapy for the COVID-19 disease. This review summarizes the potential therapeutic
options currently available for the treatment of COVID-19 including lopinavir-ritonavir,
Hydroxychloroquine, Remdesivir, Ribavirin, dexamethasone, interferon, antibodies, Tocilizumab,
Azithromycin, Piperacillin-tazobactam, Moxifloxacin, Ivermectin, Nitazoxanide, Baricitinib, and
Arbidol. This study briefly discusses the clinical trials and encompasses the dosage, efficacy, adverse
drug reactions, and possible mechanism of action of the potential treatment candidate where
applicable. The growing number of reported cases posits an exigent need for a suitable therapy for the
prevention and cure of this disease. Therefore, the study aims to provide vital information on each drug
to highlight the latest scientific research that could be helpful for better prevention/treatment of
COVID-19 disease.

Downloads

Published

2022-09-01

How to Cite

S. Areej, M. Ahmad, G.Abbas, A.Majeed, B. M.Beg, A.Iqbal, A.Basharat, R. M. Z.Mushtaq, W.Ahmad, S.Aroosa, S. Jaffery, & S. B.Shabbir. (2022). A REVIEW ON ASPECTS OF CURRENT PHARMACOTHERAPIES FOR COVID-19. Pakistan Journal of Science, 74(3), 223–237. https://doi.org/10.57041/pjs.v74i3.790

Most read articles by the same author(s)

1 2 > >>