UNVEILING THE PATHOPHYSIOLOGICAL LANDSCAPE OF COVID-19: INSIGHTS FOR NOVEL THERAPEUTIC STRATEGIES

Authors

  • Laiba Iqbal
  • Dr. Naila Iqbal
  • M. Milhan Afzal Khan

DOI:

https://doi.org/10.57041/pjosr.v4i1.1132

Abstract

The ongoing COVID-19 epidemic has emphasised the critical need for a thorough understanding of the disease’s pathophysiology environment. This article explores the complex relationship between SARS-CoV-2, the virus responsible for COVID-19, and the human body, offering light on the underlying mechanisms that determine illness susceptibility, development, and severity. The genetic, immunological, and physiological aspects that contribute to the different clinical presentations of COVID-19 using a multidisciplinary approach have been discussed. This article aims to provide significant insights that pave the way for potential therapeutic options addressing the core pathophysiological processes by deciphering these complex pathways. As the global community attempts to combat the epi- demic, a fuller knowledge of COVID-19’s molecular complexities holds the prospect of new interventions that can effectively lessen its effects. In addition, a case study featuring Quantitative Poly- merase Chain Reaction (QPCR) amplification curves and Cycle Threshold (CT) values is shown to demonstrate the significance of making an accurate diagnosis. This diagnostic approach lets physicians to distinguish between positive and negative cases, assess viral load, and offer informed treatment recommendations. By combining QPCR results with clinical data, we can acquire a greater understanding of COVID-19’s progression and influence the development of novel therapy methods. This research aims to aid the global effort to eradicate COVID-19 by elucidating its pathophysiological intricacies and employing sophisticated diagnostic techniques such as (QPCR).

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Published

2024-06-06

How to Cite

Iqbal, L., Iqbal, D. N., & Afzal Khan, M. M. . (2024). UNVEILING THE PATHOPHYSIOLOGICAL LANDSCAPE OF COVID-19: INSIGHTS FOR NOVEL THERAPEUTIC STRATEGIES. Pakistan Journal of Scientific Research, 4(1), 10–20. https://doi.org/10.57041/pjosr.v4i1.1132